Following the success of the previous symposia, we are pleased to present the 2025 John I. Ingle International Endodontic Symposium to you. Renowned experts from Australia, Canada, Greece and the United States will give the most recent advances in the field. The scientific program includes updates on hot topics in endodontics and treatment modalities, as well as an insight into the future of endodontics. This symposium promises to be yet again a most exciting event. It will provide clinicians with relevant information and tools to bring them to the next level of excellence in delivering the best evidence-based endodontic care to their patients.